This Call for Expression of Interest (CEoI) has been launched to support COVID-19 research using the strengths of EBRAINS. The call particularly seeks to support projects in the field of COVID-19-related brain-disorders and mental health issues.

The call will provide support for academic and medical research, including hospitals, or industry and pharma (SMEs and larger companies) active in COVID-19 research. Potential research topics include:

  • COVID-19 research activities that are linked to and supplement HBP/EBRAINS and other activities at European or national level in this research field, eg funded by Horizon Europe, to create synergy and increase impact through including the EBRAINS Research Infrastructure.
  • Longitudinal and cross-sectional analyses of patients suffering from neurological and/or psychiatric symptoms after infection with COVID-19, eg based on existing large cohorts.
  • Exploration of changes in brain structure and function in patients that have undergone COVID-19, eg targeting brain mechanisms underlying olfaction, memory, fatigue, depression.
  • Disease mechanisms and genotype-phenotype relationships as far as they concern the brain.
  • Short- and medium-term effects of COVID-19 and related changes on mental health and brain health, eg related to age and demographic factors.
  • Development of mathematical brain models of patients and subjects affected by COVID-19.
  • Modelling and simulation of COVID-19 disease scenarios using EBRAINS.
  • Identification, modelling and simulation of drug candidates using EBRAINS.
  • Research on middle and long-term effects of COVID-19 vaccines on the brain and mental health.
  • Developing and testing strategies for prophylaxis, based on EBRAINS.

It is highly recommended that a consortium or group of partners applies for the CEoI. At least 80% of the proposal budget must be assigned to non-HBP partners, and the HBP partners should not account for more than 20%. The successful applicants will contribute to the HBP project mission in collaboration with HBP Partners. They will also complement expertise already present in the HBP, and use a portfolio of tools and services provided by EBRAINS to conduct the proposed work.

Two proposals will be funded. Each project can request a maximum of €225,000 in direct costs, which includes a voucher of €22,500 to fund technical support for integration of project results in EBRAINS. An additional 25% (overhead rate) is also available for indirect costs. Co-funding of approximately €50,000 is requested; proposals with lower contributions must be fully justified.

Projects can last for a maximum of 16 months (1 December 2021–31 March 2023).

In the first instance, prospective applicants should email HBP researchers to discuss their proposal, its feasibility and relevance.

Funding body European Commission
Maximum value €225,000
Reference ID S9352
Category Coronavirus/COVID-19
Biotechnology and Biology
Economic and Social Research
Science and Technology
Engineering and Physical Sciences
Medical Research
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