Eve Appeal Rare Gynaecological Cancer Fund – Early Diagnosis and Prevention of Rare Gynaecological Cancers

Closing Date: 16/06/2022

Grants for UK researchers and teams carrying out studies of rare gynaecological cancers. This 2022 annual call specifically focuses on mucinous ovarian cancer.

The Eve Appeal is a UK registered charity that funds research into and raises awareness of the five gynaecological cancers (womb, ovarian, cervical, vulval and vaginal).

The Eve Appeal has established a Rare Gynaecological Cancer Fund and proposes to run a series of annual open calls for research applications. The first call is entitled Early Diagnosis and Prevention of Rare Gynaecological Cancers and focuses on mucinous ovarian cancer. This area was identified using the list of rare gynaecological cancers outlined in the Rare Neoplasms of Gynaecological Origin (RaNGO) study.

Mucinous ovarian cancer is a rare ovarian tumour that accounts for ~3% (200 women per year) of ovarian cancer diagnosis and generally effects women in the 30-50 age group. The causal factors are unknown, but genetic mutations such as mutations in KRAS gene have been reported in some cases.

Rare gynaecological cancers tend to affect younger women, and the low numbers of cases means no single doctor or centre in the UK has the sufficient experience to identify and confidently treat patients. The aim of this call is to support research focused on risk prediction, prevention, better diagnosis and early detection of these rarer gynaecological cancers so that they can be recognised and treated more quickly to improve patient outcomes.

The Eve Appeal is particularly interested in research that aims to identify:

  • Factors that put women at risk of developing one or more rare gynaecological cancers.
  • Molecular markers of these rare diseases in higher risk populations.

This could be through small-scale sample collection or development of pilot screening projects. There is a particular interest in learning whether the proposed research could benefit other rare gynaecological cancer conditions.

It is expected that the successful awardees will be in a stronger position to apply for longer-term funding (eg from UK Research and Innovation (UKRI), Cancer Research UK (CRUK) or the Wellcome Trust).

Funding body Eve Appeal
Maximum value £90,000
Reference ID S23553
Category Medical Research

Fund or call Fund