Funding for basic, clinical and psychosocial research into retinoblastoma.
The Childhood Eye Cancer Trust (CHECT) is a UK research charity dedicated to supporting people affected by retinoblastoma (Rb), a rare form of eye cancer. The mission of CHECT is to prevent sight loss and death as a result of having retinoblastoma and to support those affected by it.
The CHECT Research Fund aims to fund world-class research into the development, prevention, treatment and consequences of retinoblastoma. All aspects of research will be considered including, but not restricted to, basic laboratory research investigating disease mechanisms, preclinical experimental studies and clinical research (including, but not limited to, novel treatments, supportive therapies, epidemiology, and psychological impact of retinoblastoma).
Applications may be submitted for PhD studentships, project grants, pump-priming projects and clinical fellowships.
For the 2021 application round, CHECT is seeking applications for the following:
- Clinical research into new treatments for Rb which might improve efficacy, minimise adverse effects and maximise vision. This includes new molecules, non-chemotherapy treatments, and drug delivery techniques.
- Laboratory-based basic science research to improve the understanding of the molecular mechanisms and genetic basis of Rb. This includes study of new cellular pathways and inhibitors.
- Psychosocial research into the effects of having Rb so that ways to reduce the negative impact on those affected can be developed, including:
- The psychological impact of a retinoblastoma diagnosis on the child and/or family.
- The psychological impact of retinoblastoma treatment on the child or family.
It is expected that research will have the potential to demonstrate benefit to those affected by Rb within the short to medium term, normally considered to be five years from the grant end date.